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Bone & Cartilage Biology

Here are some of the osteology topics we at Altum Svadhaya are interested in:

1) Bone Regeneration.

The field of regenerative medicine has made substantial progress in promoting bone healing and regeneration. This includes the development of bone grafts, biomaterials, and growth factors that stimulate bone tissue repair. Additionally, stem cell therapy, particularly the use of mesenchymal stem cells (MSCs), has shown promise in enhancing bone regeneration and treating bone defects and diseases.

2) Hard tissue imaging.

Technological advances in imaging, such as high-resolution peripheral quantitative computed tomography (HR-pQCT) and magnetic resonance imaging (MRI), have significantly improved our ability to assess bone quality, architecture, and turnover. These tools allow for a more detailed and accurate diagnosis of bone conditions, monitoring of disease progression, and evaluation of treatment efficacy, leading to better personalized treatment plans.

3) Genetic factors in Bone Development.

The use of genome-wide association studies (GWAS) and other genetic approaches has uncovered numerous genetic variants associated with bone density, bone mass, and susceptibility to fractures.

4) Osteoimmunology.

The study of the interface between the immune system and bone metabolism, known as osteoimmunology, has emerged as a significant field. It explores how immunological factors influence bone remodeling, the process by which bone is continuously formed and resorbed..

5) Orthodontic considerations.

Orthodontics is a unique field of dentistry with many fingers in skeletal growth and development. We look at the differences in how this is researched and if there are any implications on treating our younger generation.

Bone biology is a unique and exciting field, in which methods of how cells relate to bone growth are rarely understood. By collaborating with various fields it becomes more clear where our emphasis must lie. There are some nuggets of information in each field, some lessons to learn in each as well.

Embryonic Stem Cells
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